Researchers provide a framework to study precision nutrigeroscience
Dietary restriction is arguably the most promising non-genetic method of extending lifespan and healthspan in many model organisms, including mammals. While researchers scramble to develop interventions that would mimic the benefits of dietary restrictions in humans (who generally have a hard time maintaining Spartan diets), the work from the lab of Buck professor Pankaj Kapahi, Ph.D., suggests that the benefits of dietary restriction often vary among individuals and even in tissues within those individuals. He and his colleagues are challenging the field to change their approach to dietary restriction and aim for precise, individualized interventions. In a review published in Cell Metabolism, they provide a framework for a sub-specialty dubbed precision nutrigeroscience, based on biomarkers affected by genetics, gender, tissue, and age.
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