Transcription initiation is a process that is essential to ensuring the proper function of any gene, yet we still lack a unified understanding of sequence patterns and rules that explain most transcription start sites in the human genome. By predicting …
Chemical modulation of proteins enables a mechanistic understanding of biology and represents the foundation of most therapeutics. However, despite decades of research, 80% of the human proteome lacks functional ligands. Chemical proteomics has advanced …
Nature Biotechnology, Published online: 26 April 2024; doi:10.1038/s41587-024-02225-zA truth-set catalog of human tandem repeats allows benchmarking of variant analysis tools…
The two NASA astronauts assigned to Boeing’s first human spaceflight have arrived in Florida for their May launch. Butch Wilmore and Suni Williams flew from Houston to Kennedy Space Center on Thursday. They will serve as test pilots for Boeing’s Starliner. The capsule is finally making its debut with crew after years of delay…
A blog by Agata D’Addato, Eurochild Head of Programmes about the CREAN Conference 2024 on Collaborative Research in Children’s Rights. The 2024 CREAN (Children’s Rights European Academic Network) conference on Collaborative Research in Children’s Rights: Fostering Dialogue Between Academia and Society illustrates how a dynamic, real-time discourse on the generation of knowledge about children...
DENVER — When combined with rHuPh20, a recombinant DNA-derived human hyaluronidase, efgartigimod, promises a new treatment option for chronic inflammatory demyelinating polyneuropathy (CIDP) , according to the results of a phase 2 multinational trial, which were reported at the 2024 annual meeting of the American Academy of Neurology…
Today’s climate-change kraken may have been unleashed by human activity—which has discharged greenhouse-gas emissions into Earth’s atmosphere for centuries—but reversing course and taming nature’s growing fury seems beyond human means, a quest only mythical heroes could fulfill. Yet the dream of human-powered flight—of rising over the Mediterranean fueled merely by the strength of mortal...