Activation of the conserved Hippo kinases by inflammasome-triggered proteolytic cleavage controls programmed cell death in macrophages

Proceedings of the National Academy of Sciences, Volume 122, Issue 5, February 2025.
SignificanceThe Hippo pathway is highly conserved in eukaryotes from yeasts to humans. While individuals with mutations in the Hippo kinase geneMST1experience recurrent infection, little is known about the role of MST1 and its homolog MST2 in innate …
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